BATF2

BATF2
Identifiers
Aliases	BATF2, SARI, basic leucine zipper ATF-like transcription factor 2
External IDs	OMIM: 614983; MGI: 1921731; GeneCards: BATF2
Gene location (Human)
Chr.	Chromosome 11 (human)
End	64,997,018 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	6,222,506 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; oocyte; ; mucosa of transverse colon; ; gonad; ; secondary oocyte; ; testicle; ; spleen; ; appendix; ; apex of heart; ; body of pancreas;
	Top expressed in
	intestinal villus; ; jejunum; ; mucous cell of stomach; ; duodenum; ; crypt of lieberkuhn of small intestine; ; colon; ; left colon; ; ileum; ; intercostal muscle; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding;
Cellular component	nucleus;
Biological process	regulation of transcription by RNA polymerase II; cell differentiation; regulation of transcription, DNA-templated; transcription, DNA-templated; myeloid dendritic cell differentiation; defense response to protozoan;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	116071
	74481
	ENSG00000168062
	ENSMUSG00000039699
	Q8N1L9
	Q8R1H8
	NM_001300807; NM_001300808; NM_138456
	NM_028967; NM_001356604; NM_001379529
	NP_001287736; NP_001287737; NP_612465
	NP_083243; NP_001343533; NP_001366458
	Wikidata
View/Edit Human	View/Edit Mouse

Basic leucine zipper transcription factor, ATF-like 2 is a protein that, in humans, is encoded by the BATF2 gene.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000168062 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000039699 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Basic leucine zipper transcription factor, ATF-like 2". Retrieved 2014-07-06.

Ma H, Liang X, Chen Y, Pan K, Sun J, Wang H, et al. (February 2011). "Decreased expression of BATF2 is associated with a poor prognosis in hepatocellular carcinoma". International Journal of Cancer. 128 (4): 771–777. doi:10.1002/ijc.25407. PMID 20473897.
Dash R, Su ZZ, Lee SG, Azab B, Boukerche H, Sarkar D, et al. (August 2010). "Inhibition of AP-1 by SARI negatively regulates transformation progression mediated by CCN1". Oncogene. 29 (31): 4412–4423. doi:10.1038/onc.2010.194. PMID 20531301.
Huang Q, Li XQ, Yang Y, Huang SA (August 2011). "[Influence of BCR-ABL inhibitor STI571 on SARI expression in K562 cells]". Zhongguo Shi Yan Xue Ye Xue Za Zhi. 19 (4): 865–868. PMID 21867603.
Su ZZ, Lee SG, Emdad L, Lebdeva IV, Gupta P, Valerie K, et al. (December 2008). "Cloning and characterization of SARI (suppressor of AP-1, regulated by IFN)". Proceedings of the National Academy of Sciences of the United States of America. 105 (52): 20906–20911. Bibcode:2008PNAS..10520906S. doi:10.1073/pnas.0807975106. PMC 2634918. PMID 19074269.
Wang C, Su Y, Zhang L, Wang M, You J, Zhao X, et al. (2012). "The function of SARI in modulating epithelial-mesenchymal transition and lung adenocarcinoma metastasis". PLOS ONE. 7 (9) e38046. Bibcode:2012PLoSO...738046W. doi:10.1371/journal.pone.0038046. PMC 3458851. PMID 23049725.
Wenig JA (May 1990). "Os trigonum syndrome". Journal of the American Podiatric Medical Association. 80 (5): 278–282. doi:10.7547/87507315-80-5-278. PMID 2366175.
Huang Q, Yang Y, Li X, Huang S (December 2011). "Transcription suppression of SARI (suppressor of AP-1, regulated by IFN) by BCR-ABL in human leukemia cells". Tumour Biology. 32 (6): 1191–1197. doi:10.1007/s13277-011-0222-1. PMID 21892628. S2CID 21309704.

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000168062 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000039699 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Basic leucine zipper transcription factor, ATF-like 2". Retrieved 2014-07-06.

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BATF2

References

Further reading

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